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Dernière mise à jour : Mai 2018

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PlatBioEng-PPF

Pilot-Scale Facilities | Bioprocess development | Pilot-scale Production | Specialised Training | Bacterial and Yeast Fermentation | Standard Operating Procedures | Downstream Operations Design

PlatBioEng-PPF

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About the Platform 

The UAB's Fermentation Pilot Plant (PPF) services are targeted to those industries that require facilities suitable for the development of bacterial and yeast fermentation processes and its scale-up for production at a pilot scale. The PPF has collaborated with companies of diverse sectors, including Pharma and Veterinary (antigens, toxins for diagnosis, pharmacologically active proteins, plasmid DNA), Fine Chemistry (optically active molecules, enzymes), Food and Agriculture (starters, fungicide, bactericide, food additives) or Cosmetics. The Plant has the facilities and the equipment required for the development of continuous, batch or fed-batch culture processes, as well as for carrying out of primary downstream operations.

Offer

  1. R+D+I of biotechnological processes, including: Design, development and optimisation of bioprocesses Culture medium design. Growth and production kinetics. Analytical methods implementation. Culture strategies study. Scale-up development. Downstream development Training of specialised personnel for biotechnological companies.
  2. Production at pilot-scale: Production of significant quantities of biotechnological products. Production under Standard Operating Procedures (SOP).
  3. E. coli recombinant protein production platform: Proprietary strain and vector antibiotic free expression system. Fast gene to protein workflow. High cell density fermentation platform.

More Info

Key equipment of the PPF:

  • 2-5 L lab-scale fermenters
  • 2x50 L and 1x250 L pilot-scale fermenters
  • Pilot-scale disk centrifuge (8800g)
  • Pilot-scale tubular centrifugue (15000g)
  • Tangential flow-filtration system Sartocon 2
  • Filtration units for 30" filtration cartridges
  • Pilot-scale cell disruption system up to 40 kpsi
  • Molecular biology equipment: electrophoresis, PCR

Units of access: 2 Months

  • Quantity offered: 1
  • Total offered: 2 months
  • Type of access: on-site

SERVICE INSTALLATION CODE: ES_UAB-PlatBioEng-Fermentation

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The Universitat Autònoma de Barcelona (UAB) is one of the major public universities in Spain and coordinates the scientific and technological UAB-CIE Sphere, which comprises science and technology services, research centres, institutes and university hospitals. Within the UAB, the Department of Chemical, Biological and Environmental Engineering (DEQBA) is a reference of Southern Europe in the fields of Biological Engineering and Environmental Technologies.

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