Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal


MetaToul Fluxomics

13C Fluxomics | Flux Calculation | Modelisation | Metabolic Fluxes

MetaToul Fluxomics


About the Platform 

The MetaToul - Metabolic Networks platform dedicates its activities to the functional analysis of cellular metabolism. For this, the platform develops and applies methodologies combining mass spectrometry and nuclear magnetic resonance for the analysis of metabolic networks: 

- Quantitative targeted analyses
- Identification of metabolic pathways by isotopic labeling (13C-Metabolomics)
- Measurement of metabolic fluxes (13C-Fluxomics)
- Modeling of metabolic systems (Flux calculation)


Fluxomics is the measurement of the real speeds of metabolic reactions in the integrated biological system (intracellular/intratissular fluxes). 

There is no direct method to measure intracellular fluxes in a cell or tissues. The most relevant indirect approach is based on isotope labeling strategies, here 13C, coupled with fine analysis (measurement of "isotopomers") of isotopic incorporation into metabolites, performed either by mass spectrometry (MS) or by nuclear magnetic resonance (NMR). It leads to obtain flux maps that represent the quantitative distribution of the fluxes (here carbon) in the metabolic network of the biological system studied. 


- Macrokinetic knowledge : consumption and production rates, biomass composition - Metabolic network knowledge : topology, enzymatic reactions, carbon transitions
- Intracellular pools from central metabolism
- Validation of sampling protocols for isotopic profiling by MS or NMR

More Info

The platform is ISO9001 NFX-50-900 certified and is part of the National Infrastructure of Metabolomic and Fluxomic METABOHUB.

Units of access: Flux Map

  • Quantity offered: 2
  • Total offered: 2
  • Type of access: remote/on-site



LISBP (The Biological Systems and Biochemical Engineering) is a Joint Research Unit (UMR) associated with INRA, CNRS, INSAT and located on the INSA-Toulouse Campus. Internationally recognised, the LISBP stands out as a pioneer for the innovative way it associates Life Sciences and Engineering Sciences, as well as for its advances in fundamental and applied Biology, Microbiology, Microbial Physiology and Metabolism, Engineering, Fermentation and Processes. The LISBP research work has very large applications in Industrial Biotechnology such as Bioenergy and Green Chemistry, Water Treatment, Food Processing and Health.