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BIOKET 2020 10-12th March 2020 | IBISBA workshop 12th March 2020

Lille Grand Palais | 1 boulevard des Cités Unies - 59777 Lille, France

BIOKET 2020 10-12th March 2020 | IBISBA workshop 12th March 2020
Join us for the workshop on IBISBA within the global context of biofoundries and end-to-end bioprocess development

Guest Speakers

Prof. Paul FREEMONT | Imperatial College London, UK
Dr. Sunil Chandran | Amyris, USA

Registration

www.bioket.eu

The Foundries

that powered the industrial revolution took molten metal and cast it into items of different shapes that in turn became the parts of complex machines and industrial processes. Similarly, biofoundries aim to be places where DNA is combined to form bioparts that, once integrated into living microbial cells, will drive biological manufacturing processes. Unlike the foundries of old, biofoundries rely heavily on automation, using informatics and robotic systems to reproducibly design, build and validate complex molecular machineries. The recent appearance of biofoundries is linked to the growing importance of synthetic biology, a term that covers the use of advanced approaches for the design and construction of complex biological systems using the 'design- build-test' framework, borrowed from the information systems engineering area. Synthetic biology has greatly benefitted from systems biology, which provides ‘omic-scale’ data (DNA sequences, genome-wide metabolic maps, fluxomic data etc) that drives the design process, and from advanced DNA synthesis and microfluidics, which together provide the technology basis for this activity.

Using synthetic biology, researchers aim to accelerate the development of industrial biotechnology. However, it is widely recognized that while synthetic biology is making lab-scale production of molecules more tractable, it is still debatable about the extent to which synthetic biology is producing impact at the industrial scale. This is because, to achieve impact at the industrial scale it is necessary to go beyond design of the biocatalyst (the enzyme or the microbial cell), conceiving the whole bioprocess, including the way in which the target molecule will be extracted and purified.

IBISBA is an emerging, European-based distributed R&D infrastructure that integrates biofoundry operations into the wider framework of end-to-end bioprocess development, the aim being to deliver industry-ready processes.

The workshop

During this 3-hour session, experts will first set the scene and help us to appraise the current state of play in the biofoundry area and examine how biofoundries are likely to evolve in the future. Afterwards, the IBISBA concept will be spotlighted, looking at its biofoundry activities and how these fit into the wider framework of end-to-end bioprocess development which is being promoted by IBISBA. Moreover, we will examine some of the challenges related to injecting industry constraints into early phase bioprocess development. This session will bring together leading researchers from the IBISBA network of research facilities, a member of the Global Foundry Alliance and an industry player involved in the development of commercial biofoundries.

The workshop will be a lively combination of talks and debates in which the audience will be invited to play a full, active role providing feedback on their expectations regarding R&D infrastructure services, such as those proposed by IBISBA.

Practical details

The workshop will take place at 2-5 pm on the 12th March 2020 in the framework of the BIOKET conference. Registered BIOKET conference attendees are free to participate in the workshop as part of their conference package. Other participants can register free of charge for a 1-day conference pass.

Download the leaflet